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ADT options ?

I currently am going through a rise in PSA less than two yrs after having my prostate removed. Pet scan shower zero in prostate bed area but a small localized nodule on one of my lymphnodes. They are now recommending radiation along w/ ADT . So I have been reading up on ADT as from reading posts on the forum I was really hoping to avoid this therapy but as it is the industry standard for a mestasized PC no luck. But have been reading about a pill form of Relugolix (Orgonyk) that sounds a lot better than the standard Lupon injection. It is a daily pill that actually inhibits Testosterone production in your body and starts fast and ends fast when your therapy is over.....looks like this is going to be the new standard or maybe already is. It is also given with a second drug that inhibits receptor sites (called a doublet therapy....two drugs working together to acheive desired results) or three drugs for more advanced PC ( called a triplet ). I have not read here on the forum much about this newer drug therapy and was looking for some feedback from actual users as to side effects etc. Mahalo Kevin

  1. Hey there - thanks for sharing here. Sounds like you're exploring your options and doing your research which is great. I'll of course welcome members of the community here to share with their experiences but I did want to share this forum where people have shared some of their experiences with Relugolix, in case you wanted to jump in there or just take a look at what people have shared previously. Hope this helps! Here's the link to that forum discussion: https://prostatecancer.net/forums/relugolix-orgovyx-how-has-it-affected-you.

    - Jake (Team Member)

  2. Hi Kevin (). On top of the excellent information from Jake, I just want to note concerning combination therapy that your research appears correct that this is primarily in use for more advance metastatic cases. Our contributor Tony had a conversation here with Professor Nicholas James, Chief Investigator on the STAMPEDE trial, where they touch on this: https://prostatecancer.net/living/interview-stampede-trial. Also, here is a newer research article on the topic: https://ascopubs.org/doi/10.1200/OP-25-00050. Hopefully your case would not require this, but hoping you can have a conversation with your doctor on whether the Relugolix would be right for you. Best, Richard (Team Member)

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